I use Wilbur+18 and Tarlak for all titans (except red and green rare titans). The other three heroes are:
Boldtusk+18 - Falcon - Elena+7
Telluria+18 - Hatter+7 - Little John+18
Ariel+7 - Magni+7 - Lepus+18
Jackal+18 - Joon+13 - Neith+6
RigardC+7 - Seshat+18 - Victor
You want Miki or Tarlak in there too.
I get better scores with PiBs, his attack stat is much higher than BT even with emblems and CBā¦ Try it both ways and see.
Miki/Tarlak, Wilbur, Falcon, PiBs/BT, Azlar (tiles)
If you have enough emblems on GM or Kestrel to have higher attack stats than Azlar then swap them in instead of him.
I get better scores using Almur instead of Telly.
Iāve always used Buddy, thoughā¦ Find your lowest tile damage out of whatās left and try him instead.
Athena kicks ā ā ā .
If Grimm is emblemed enough to have higher attack than Isarnia, no - if her attack is higher then run her instead.
Kirils tiles are so-so, but he adds the buff which Raffaele wonāt (also with so-so tile damage).
These are great lineups! I have many of these heros excep Ariel, Lepus, and Victor. The biggest issue for me are the talent levels per hero. Iām a ways off from those levels. Plus, my troops are at lvl 21 which higher levels Iāll aide in survivability and mana refresh times.
Thank you @ThePirateKing for this insight into your setup!
This is perfect @BubblesUK! Thank you!
I had been using PiB prior, but other threads had suggested that BT would be better. This, I switched PiB for BT. Iāll swapped him back.
I just pulled Almur during the last Valhalla event. Iām leveling him now and will try him as soon as he is ready. I was thinking about swapping out Telluria, but I felt the +16 talent level was better than a non-leveled Almur.
Iāll get Athena and Isarnia into the lineup as soon as they are leveled. I moved Raffaele ahead of both as I needed more 5* healers.
This is great info! Thank you @BubblesUK! Iām stoked to try these changes out! My goal is to consistently do 80k to 100k+ attacks per flag.
Miki only increases ānormal attackā aka tile damage. So it doesnāt really matter if you fire him first or last. The only concern is the animation time as @BubblesUK mentioned so I would still fire Miki first.
WTH 500 dmg from minion strikes 
! Does Freyaās minions get buffed by Miki as well? I guess itās worth having Freya on the team despite the time taken up by minion strikes, especially since Freya has decently high attack.
My only other question here is with the Dark team. The animations for Miki, Freya and Clarissa, will slow down the play and lower the score. Is it wise for me to have all 3 in the same lineup?
I think it should be ok. Just hit all of them in quick succession. One thing I do when there are a lot of animations going across the screen is tap the āautoplayā button and then untap it. It works well when there isnāt an ideal move and it will quickly automatically make a match so I can think about the next move Iām going to make. I only do this when there isnāt a match lined up over the titanās weak spot and when there arenāt a lot of tiles of my heroās color.
Really good advice! I never thought about using the auto-play to give me a second to look the board over for a better move. Great tip! Thanks @B1gHeadAss!
Great info here, thanks for asking and for all the replies 
Itās the m$llion dollar question that folks either couldnāt or wouldnāt answer. @ThePirateKing, @BubblesUK and @B1gHeadAss, did a great job giving me clarity on the topic. Thanks all!
I think no one should rely on Freyaās minions doing ā3-500ā damage everytime. They are doing some noticeable damage, but only at smaller titans and only with additional buffs active. Facing a 14* armored hydra those minions will rarely reach 300 damage, but more something like 150-200ish. So in my opinion you should consider if this is worth the time it costs at higher titans.
I think itās much better to figure your next move before starting all those annoying animations, so that you can do it although you canāt see most parts of the board. Tapping autoplay seems like the worst thing to do to me, as this can completely destroy your board manipulation and preparation (it will automatically fire bombs and diamonds if there is any and will most likely result in any nonsense move). I personally would always wait a second or two instead of tapping the autoplay button in these situations.
But anyway, everyone needs to figure out what works best for them. 
@TriNitro Good feedback. I was planning to use the following Dark team initially
Miki-Wilber-Kunchen-Domitia-Clarissa
Once I level Seshat, I was going to replace Clarissa. I was going to play around with Freya once I have her leveled to see if she adds more value than Domitia. Prior to the feedback from this thread, I had Tiburtus in the lineup instead of Wilber. I have also tried Proteus, but I have trouble keeping him alive long enough to be useful.
What lineup would you suggest?
Dispel - Attack up - Def Down - Mana control - AoE/ Snipers
This the the rule of thumb team order I follow pretty much everywhere.
Only exception buffs which have a chance to miss, like Wu ā¦ they go last so the buff applies to tiles and not specials where the miss rate doesnāt hurt so much.
Titan is mostly a tile damage plus firing specials in correct order game. Tile damage is easy to see, so Iām going to break this down by special skills:
Miki - +130 to +170 Attack up
Wilbur - +63 Def up allies, -44 Def down enemy, shared damage
Kunchen - Heal, -34 enemy def down, +46 ally anti-holy def up
Domitia - hit, dispel, +94 anti-holy def up
Clarissa - Fast hitter, poison dot, special skill def up
Seshat - Hitter, dispeller, minion
Freya - Raven minion, +30 ally def up
Tiburtus - enemy Def down -34
Proteus - Mana control, poison dot
So how to build the team:
Use Wilbur+Domitia - Wilbur is the highest enemy def down. He also gives ally def up which stacks with Domitiaās high anti holy ally def up. Domitia is also a hitter.
Use Kunchen to get a little bit of both and save a spot.
Depending on which option you chose, you can play around other spots between Clarissa, Freya and Proteus, and see which works best for you. Clarissaās special skill def up gives her an edge over the other two.
So, I would try
Miki - Wilbur - Domitia - Seshat - Clarissa
Or
Miki - Kunchen - Seshat - Clarissa - ? (Maybe Freya? You need a sturdy hero because your ally defence buffs are lower. But you do get better color stacking damage)
You could pair Wilbur and Kunchen, but it would be a pain to remember to fire Wilbur AFTER Kunchen to overwrite the higher enemy def down buff. And letās face it, fast Titan battles makes it easy to skip up on the small stuff. Similarly, you could pair Kunchen-Domitia as well, and thatās a decent pairing as long as you fire in order.
Side Note: 4* Cheshire Cat is the only purple with a +44 enemy def down for yellow. Itās not an elemental def down though. 5* Guardian Panther is the purple enemy def down.
Edit: There are two purple heroes with Mindless Attack - Merlin and Alfrike. Both make the Titan hit itself and reset the mana bar. Higher the Titan, more the damage. And itās always hilarious. Using mana control with mindless attack can be very effective but timing the attacks takes effort and some practice.
@BubblesUK I had the same thoughts on Jott but so far not yielded the results I thought they would. Not 100% sure why itās not working as well as I thought it would do either as on paper itās very good. Just not translated yet.
With Wilbur you can keep him going easy enough but I guess maybe I havenāt had the truly optimal board for it yet.
Sometimes the board is so bad and there is literally only 1 or 2 possible moves that it saves time using autoplay for 1 second. Ofc, I usually donāt use it and have a move planned despite the animations covering the board.
Excellent feedback @Circe! You listed some create points.
Seshat is a must for the lineup.
I need to set the Hero Team order correctly to match the launch order. Thus,
Miki-Kunchen-Wilber-Domita-Clarissa
Or
Miki-Kunchen-Wilber-Seshat-Clarissa
Miki-Kunchen-Wilber-Seshat-Alfrike
Great info @Circe! Thanks!
Well, i have Alfrike+20 but would not use her for titans. I understand that mindless attack seems like a smart thing to have on a titan. But as long as you bring Miki in that lineup, you should be able to never let the titan fire its special.
In addition to that, Alfrike was most likely designed as a tank and does pretty good in that position, but she has horribly low attack stats (mine has a squishy 700 at +20) and thus lowers the tile damage on titans.
Remember: its all about speed and tile damage.