As a point of interest… I’d disagree slightly on Locke.
I put her aside expecting her to be useless on later stages - then at the last few levels I was running short on healing and wound up resorting to green mono, which meant Locke went in.
I was expecting her DoT to get limited to it’s start and therefore provide almost no damage… On the contrary, it was limited to it’s end meaning it starts at the high damage end - much more useful!!!
(For those who aren’t familiar, Locke’s DoT special is unusual because it starts from very low damage and gets higher every turn, culminating in a 400+ chunk taken off on the final turn… So starting later and higher up the scale was positively helpful!).