I think it comes down to which items you need from these quests. Don’t get too hung up on the EXP value: levels don’t contribute a whole lot to your overall strength.
Rare quests: do them all if you can! These are arguably the best sources of ascension items in the game.
Gem quests: yes, if you value gems (who doesn’t?)
Recruits I & II: once you have TC20 you will be doing all of these. Heck, even if you’re dedicated to TC13, these are great. Recruits II also used to have an epic troop token as a hidden reward, but based on the last 6 iterations this has been axed. Maybe it’ll come back some time.
Battle items II: sometimes has a raid flask posted on the 3rd stage, but that also used to be a hidden reward. I generally do it just to check.
Crafting items I & II: some of these ingredients will start to be in short supply as you become more dedicated to titan attacks, and crafting battle items. Watch for those metal ores, hardwood lumber, and crypt mushrooms.