Alright @JekylandHyde I have only looked at your specific two examples. I think that there are better options to use for the final striker than Buddy due to his stupid low attack stat but that’s by the by… You can sub in any other hero and the outcome will be the same (in terms of the firing order).
Scenario 1 – Almur > Buddy > Mist > Buddy
Total damage to target = 2,244
Scenario 2 – Almur > Mist > Buddy > Buddy
Total Damage to target = 2,449
So the final strike is the same damage either way (obviously). The main difference comes from when / what is affected by Mist’s damage really…
In scenario 1, both Mist & Buddy #1 strike are affected only by 1x debuff.
In scenario 2, only Mist’s strike is affected by 1x debuff… Buddy #1 strike is affected by both Almur & Mist’s debuff.
Scenario 3 – Almur > Mist > Buddy > Little John (+CB)
As a case study to show how much better it would be if you included someone with a better attack stat I have used Little John (with costume bonus) who has equal highest attack stat of the 4* green heroes.
Total Damage to target = 3,084
Scenario 4 – Almur > Mist > Buddy > Gadeirus > Little John (+CB)
Final scenario if you were to include Gadeirus into the equation:
Total Damage to target = 5,771
Click for alternate spot testing of Gadeirus
Firing after Mist but Before Buddy (buffing Buddy also)
Total to target = 5,779
So basically the same… But have to fire out of order (left to right) which is annoying.