I raid mono almost exclusively now and love the challenge of the 2 or less starting tile or the starting horizontal 3 tiles to three heroes and then nothing boards.
You begin to make moves on the probability that your needed tiles will drop and what you find, if you work the patterns right, is that they will eventually fall where you intend them to be.
You pick an enemy hero that won’t annihilate you (Aegir, riposte or healer tanks are my absolute best friends) and get to work. The Azlars and Isarnia tanks of the world fry you in your tracks if your board and/or subsequent tile drops aren’t favourable.
The math doesn’t lie and the technique is like card counting and less like gambling (or summoning heroes).