Auto play map
4* 4.70 Melendor, Grimm, Scarlett, Wu Kong, Rigard can auto play a surprising number of season 1 and season 2 stages. But they are slow.
I have 4 teams set up just for optimal farming- rainbow 3e farming; double purple no yellow for 3e & 4e farming; double red no green for common quests; double yellow no purple for farming Rugged clothes in Season 2.
Tip: you can tap a boss, while auto play is running, to target that enemy with all special skills.
Auto play titan
But titans are very unforgiving. I have never lasted 90 seconds auto playing a Titan. But poor damage on the titan is better than no damage and wasting titan energy.
Brain hiccup
Sometimes your brain just can not find a match when fighting a titan.
Tap the auto play button, after the tiles start to move, tap auto play off.
This works because any board with out a match gets shuffled and the longer you go without finding a match the more your sympathetic nervous system restricts your visual making pattern recognition more difficult. Once a match is made by the computer, your parasympathetic nervous system kicks in and relaxes you Vision to a wider field of view.